91猎奇

Proteomics technologies have become an integral part of modern-day scientific research.聽 It is an essential component of systems biology alongside the genomics, transcriptomics, and metabolomics. Furthermore, proteins are, by far, the most 鈥榬eactive鈥� part of the cell as they execute and control the majority of biological processes. The advent of high-performance proteomics makes it possible to study protein expression and regulation on a systems-wide scale. The technological developments made over the past decade have allowed the development of tools to interrogate the primary protein sequence, post-translational modifications, and secondary, tertiary, and quaternary structure. Advances in mass spectrometry and protein chemistry now allow the characterisation of the proteome, its interactions with other biomolecules within cells and tissues, in a quantitative manner with temporal and spatial resolution.

The 91猎奇 Advanced Lecture Course ‘Advanced proteomics’ / contains educational talks, interactive tutorials, and workshops covering technological basics, current best practices, and future developments given by leading academic and industry experts.聽 The extracurricular activities and the social events in the gothic cellar vault at our venue have proven to be an excellent environment for student and speaker interactions. The registration fee includes access to all lectures, workshops, and social activities, and accommodation (two people sharing a room), as well as all meals. Our summer school is designed to provide graduate students and young postdoctoral scientists from academia and industry with deep insights into state-of-the-art proteomic technologies and applications in the life sciences.

Organizers: Kathryn Lilley, Britta Eggers, Christina Ludwig, Caroline May, Shabaz Mohammed, Jesper Olsen

Cancer research is still pushing scientific boundaries and new developments and insights are entering the clinic at increasing pace. Most of the recent clinical successes come from a better understanding of basic processes that govern the malignant behavior of the cancer cell itself, as well as the way the cancer cell interacts with cells in its environment. Consequently, we see that new inhibitors of these processes, are entering the clinic very rapidly.

The molecular mechanisms by which cancer cell behavior is controlled are intensively studied in modern biology. In this Joint 91猎奇/EMBO Lecture Course ‘Cancer research; from fundamental insights to clinical application’ (co-sponsored by )聽held in Spetses, Greece, we are bringing together a number of true experts in the field of cancer research, from basic to clinical oncology. This course will cover cancer signaling and metabolism, genome instability and tumor evolution, the tumor microenvironment, and novel ways of drug development. Finally, the application or translation of this knowledge into the clinic will be discussed by the speakers.

This joint course website is under construction. Please monitor the for when the link becomes available.

Organizers: Boudewijn Burgering, Ren茅 Medema

The 91猎奇 Workshop ‘Biochirality across scales’ will be the first comprehensive interdisciplinary meeting dedicated to chirality in biology, spanning scales from molecules to whole organisms. Chirality, the property of non-superimposable mirror asymmetry, is a fundamental organizing principle in life, influencing amino acids, sugars, nucleic acids, cytoskeletal polymers, supramolecular assemblies, and organismal traits such as organ handedness and brain lateralization.

Despite its central role, chirality has so far been studied only in fragmented contexts, leaving a critical gap in understanding its integrative impact across biological systems.聽This workshop brings together leading researchers from biochemistry, molecular biology, structural biology, neuroscience, and biomedical fields to provide a holistic perspective on biological chirality.

The program emphasizes accessibility and training for early-career scientists, with clear, concept-focused lectures, interdisciplinary sessions pairing senior leaders with young investigators, and interactive formats including 鈥淐offee Break / Whiteboard Discussions鈥� and extended 鈥淐ome with Your Question鈥� poster sessions.聽Innovative features, such as 鈥淢y Science in 3 Minutes鈥�, will allow ten selected young investigators to present their research on a single slide in three minutes, with a prize for the best presentation. Poster sessions will encourage participants to present both results and open questions, fostering dialogue, mentorship, and interdisciplinary engagement.

By combining cutting-edge science with structured training, networking, and collaborative opportunities, this workshop aims to inspire dynamic exchange, promote mentorship, and cultivate the next generation of molecular life scientists, reflecting 91猎奇 mission of supporting scientific excellence across Europe.

The course website is under construction. Please monitor the Advanced Courses calendar for when the link becomes available.

Organizers: Agnes Banreti, Maximilian Furthauer, Uwe Meierhenrich, Jean-Pierre Mothet, Stephane Noselli

The will take place in the island of Spetses, Greece, 3鈥�8 September 2026. It will bring together experts to teach the basics and discuss the state-of-the-art in the highly relevant and interconnected topics of liver (patho)physiology, hepatocyte metabolism, liver fibrosis, hepatocellular carcinoma, and the development of novel model systems.

A disbalance in the synthesis, secretion, and uptake of lipids can cause MASLD (metabolic dysfunction-associated steatotic (fatty) liver disease), which can lead to hepatic inflammation (MASH), fibrosis, cirrhosis, and hepatocellular carcinoma. MASLD has a worldwide prevalence of 30%, with 20% of MASLD-affected individuals developing MASH and ~20% of this group developing liver cirrhosis over the next 3-4 decades. Increases in obesity worldwide mean these numbers are expected to rise, so preventive measures and drug development are urgently needed.

In this context, newly developed model systems representing key aspects of liver function and liver structure are helping the elucidation of molecular and cellular pathways involved in MASLD, and ultimately allowing the identification of novel druggable key nodes. The course is open to PhD students and early-career researchers and will be organized in an informal setting with many sessions and activities scheduled to stimulate interactions between the participants and the speakers.

Additional information on the course can be obtained from this 聽by the course organizer.

Organizers: Bernd Helms, Benedetta Artegiani, Delilah Hendriks, Panu K. Luukkonen

The will bring together international experts and early-career researchers to explore the extracellular matrix (ECM) and its interplay with the immune system and tissue-associated microbiome 鈥� three interconnected biological systems that shape tissue homeostasis, regeneration, aging, and disease, yet are often studied independently.

Participants will be introduced to state-of-the-art concepts and experimental approaches through a programme of introductory and advanced lectures, discussion sessions, and meet-the-expert activities delivered by leading scientists in ECM biology, immunology, microbiome research, and regenerative biology. The scientific programme will address:

• Structure鈥揻unction relationships of ECM macromolecules and their roles in tissue assembly
• Mechanisms of ECM remodeling and the influence of matrix-modifying enzymes on immune regulation
• Microbiota-driven modulation of inflammation and ECM dynamics, ECM-mediated signaling, stem cell niche regulation, and tissue regeneration
• Tools and models for probing microenvironmental interactions, including organoids, gnotobiotic systems, and decellularized scaffolds
• Systems biology approaches to integrate ECM, immune, and microbiome signaling networks

Alongside the lectures, the course will feature poster sessions, small-group discussions, and career-development activities. Mentoring and networking events will provide opportunities for participants to build collaborations and interact closely with faculty across disciplines.

What distinguishes this course is its holistic, mechanistic perspective on ECM鈥搃mmune鈥搈icrobiome crosstalk, integrating biological systems that are typically examined in isolation. Building on the strong legacy of previous 91猎奇 ECM courses (2007鈥�2023), which have generated highly cited The 91猎奇 Journal MiniReview Series and Special Issues, this course aims to equip participants with the conceptual and technological tools needed to advance research in this rapidly developing field. 91猎奇 Youth Travel Fund (YTF) grants will be available.

Organizers: Nikolaos Afratis, Nikos K. Karamanos, Valerio Izzi, Laurent Duca, Martin G枚tte

Redox homeostasis is a prerequisite for human health, in which the physiological levels of nonradical reactive oxygen species function as the primary second messengers to modulate physiological redox signaling by orchestrating multiple redox sensors. However, redox dysregulation leads to biomolecule damage and subsequent occurrence of various diseases such as cardiovascular pathology, cancer and neurodegeneration.

The , jointly delivered with the , aims to tackle the intricate redox signaling network that has evolved around cellular metabolism, generation of radical species, and cellular responses that affect growth and death. The speakers will discuss different aspects of redox signaling involved in both physiological and pathological conditions and how dysfunction of this complex signaling network can be targeted to prevent/slow disease onset and progression. Further, different model systems as well as methodological approaches, including transcriptomics, metabolomics, and proteomics, will be discussed to provide students a wider perspective of questions, models, and approaches that can be developed for future studies.

The program offers a diverse array of activities, including training lectures, poster sessions, short presentations by all participants, and ‘meet the expert’ sessions that provide young scientists with the opportunity to engage directly with leading international experts in redox biology.

The course will target early-career researchers (ECRs) from different areas of basic biological sciences and medicine, primarily experienced PhD students and post-doctoral level scientists within 5 years after completion of their doctorate. ECRs will be selected primarily based on their qualifications relevant to the course content, their potential to contribute to the breadth of science, and the benefit they are likely to obtain for their future careers, while ensuring a broad participation from different 91猎奇 constituent countries and a focus on equality and diversity.

Image: neurons stained with DCF, for ROS assay; from lab of M. Perluigi.

Organizers: Marzia Perluigi, Fabio Di Domenico, Niki Chondrogianni

The will be held in 12鈥�18 October 2026 on the island Spetses, Greece. Brain function depends on the exquisitely controlled spatial and temporal release of neurotransmitters, which are stored in synaptic vesicles (SVs). In addition, synaptic function relies on profound cargo and lipid flux and on organizational principles to recycle and enrich distinct sets of proteins/lipids in local functional and dynamic environments. Recent advances in techniques such as high-resolution imaging, in vitro reconstitution, electrophysiology, molecular modelling, and biophysics have provided remarkably detailed and unsurpassed insights into the molecular components and mechanisms, structural architecture, signaling pathways and pathogenesis underlying neurotransmitter release.

This course aims to provide an integrated perspective on synaptic vesicle dynamics, bringing together experts at the forefront of closely related and highly relevant topics including membrane trafficking, lipid dynamics, neuronal exocytosis, and the organization of supramolecular structures and molecular condensates. The talks will emphasize molecular mechanisms, structure-function relationships, molecular causes of neurological disease, and state-of-the-art technologies. In an informal setting, poster sessions, oral presentations, and casual meet-the-expert rounds will stimulate interactions between students, postdocs and lecturers, establishing scientific and personal networks.

Organizers: Thomas S枚llner, Bernd Helms, Felix Wieland

The will take place 19鈥�22 October 2026 in Budapest, Hungary. The course continues the tradition of the Danube Epigenetics Conference series, which has grown into a recognised international brand in the field of chromatin and epigenetics research.

The 2026 event will explore key themes in modern epigenetics, such as epigenetic memory and chromatin dynamics, noncoding RNAs, 3D genome architecture, and gene regulation; germline reprogramming and developmental epigenetics; and AI-powered multiomics and single-cell technologies.

The course will also include an AI & Data Analysis workshop, poster sessions with integrated flash talks, roundtable discussions, social events, and dedicated networking time with speakers. There will be affordable access for your scientists, especially from Central and Eastern Europe.

Additional information can be obtained from this 聽by the course organizer.

Organizers: Ferenc Mueller, Petra Hajkova, J. Andrew Pospisilik, Celia Martinez-Jimenez, Lorant Szekvolgyi